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In his seminal 1955 paper he defined these factors as: "Patients showing various combinations and permutations of these six sexual variables may be appraised with respect to a seventh variable: 7.Gender role and orientation as male or female, established while growing up." "all those things that a person says or does to disclose himself or herself as having the status of boy or man, girl or woman, respectively.Money introduced numerous definitions related to gender in journal articles in the 1950s, many of them as a result of his studies of Hermaphroditism.Money's definition of gender is based on his understanding of sex differences among human beings.According to Money, the fact that one sex produces ova and the other sex produces sperm is the irreducible criterion of sex difference.However, there are other sex-derivative differences that follow in the wake of this primary dichotomy.More recent academic studies have criticized Money's work in many respects, particularly in regards to his involvement with the sex-reassignment of David Reimer and his eventual suicide.

In 2002, as his Parkinson's disease worsened, Money donated a substantial portion of his art collection to the Eastern Southland Art Gallery in Gore, New Zealand.In his studies of hermaphrodites, Money found that there are six variables that define sex.While in the average person all six would line up unequivocally as either all "male" or "female", in hermaphrodites any one or more than one of these could be inconsistent with the others, leading to various kinds of anomalies.It includes, but is not restricted to sexuality in the sense of eroticism.Gender role is appraised in relation to the following: general mannerisms, deportment and demeanor; play preferences and recreational interests; spontaneous topics of talk in unprompted conversation and casual comment; content of dreams, daydreams and fantasies; replies to oblique inquiries and projective tests; evidence of erotic practices, and, finally, the person's own replies to direct inquiry." Money made the concept of gender a broader, more inclusive concept than one of masculine/feminine.